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Sports · October 28, 2026

New study estimates 75 percent of former NFL players who died from 2008 to 2023 had CTE

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A new study published in JAMA Network Open estimates that 75% of former NFL players who died between 2008 and 2023 had chronic traumatic encephalopathy (CTE). Led by researchers from Boston University, the study represents the highest prevalence estimate to date for the neurodegenerative disease, which is linked to repetitive head trauma. While previous studies using donated brains found rates as high as 99%, researchers noted those figures were influenced by selection bias from families who suspected cognitive issues. This latest analysis aimed to provide a more representative view, though experts clarify that not all individuals with physical signs of CTE will develop clinical symptoms or dementia.

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Reported by multiple outlets

  • A study published in JAMA Network Open estimates that 75% of NFL players who died in a recent 15-year span had CTE.
  • The 15-year study period spans from 2008 to 2023.
  • The research was led by or involved researchers from Boston University.
  • CTE is a neurodegenerative disease linked to repetitive head impacts.
  • CTE can only be definitively diagnosed after death.

Reported by only some outlets

  • NBC News reports that an estimated 27% of the former players in the analysis had dementia.
  • NBC News notes that a study published in August by the same group estimated one-quarter of NFL players who died in a five-year span had CTE.
  • NBC Sports identifies researchers from Mass General Brigham and the Concussion & CTE Foundation as contributors to the study.
  • CNN mentions that CTE has also been detected in military personnel and victims of domestic violence.
  • NBC News reports the study was published on Wednesday, October 28, 2026.

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