Entertainment · October 21, 2026

Christina Applegate tearfully reveals multiple sclerosis misdiagnosis

3 sources →

Christina Applegate revealed on her podcast "MeSsy" that she was recently informed she does not have multiple sclerosis (MS), a condition she was originally diagnosed with in 2021. Despite the news that she does not have the disease, Applegate expressed emotional distress, describing herself as 'back at square one' and finding the situation confusing and unnerving. She had spent several years as a public advocate for MS awareness and recently published a memoir detailing her experience with the illness.

Read the original coverage

CBS NewsMainstream
Christina Applegate tearfully reveals multiple sclerosis misdiagnosis
Read at CBS News ↗
Fox NewsMainstream
Christina Applegate says she was misdiagnosed with MS and is now 'back at square one'
Read at Fox News ↗
The GuardianMainstream
Actor Christina Applegate reveals she was misdiagnosed with multiple sclerosis
Read at The Guardian ↗

Reported by multiple outlets

Christina Applegate was originally diagnosed with MS in 2021.
She announced on her podcast 'MeSsy' with Jamie-Lynn Sigler that she was misdiagnosed.
Her doctor told her 'Congratulations, you don't have MS.'
Applegate described the news as unnerving and felt she was back at square one regarding her health.

Reported by only some outlets

Applegate is 54 years old.
She published an emotional memoir in March 2024.
She was a prominent advocate for MS awareness following her initial diagnosis.

About these outlets

CadNews does not determine absolute truth or endorse political viewpoints. It compares publicly available reporting, identifies shared facts, highlights framing differences, and flags uncertainty.