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Sports · October 25, 2026

49ers injury news: Christian McCaffrey questionable vs. Falcons

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San Francisco 49ers running back Christian McCaffrey suffered a thigh injury during the first quarter of Sunday's game against the Atlanta Falcons. McCaffrey spent time in the medical tent and locker room during the second quarter and was initially listed as questionable to return. Despite the injury, he returned to the field for the start of the second half, though with a diminished workload. The 49ers ultimately lost the game to the Falcons, marking their first loss of the season. Following the game, McCaffrey expressed frustration regarding the timing of the injury but reassured reporters that he expects to be fine for future play.

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Reported by multiple outlets

  • Christian McCaffrey sustained a thigh injury in the first half of the game against the Falcons on October 25, 2026.
  • McCaffrey was listed as questionable to return during the second quarter.
  • McCaffrey returned to play for the start of the second half.
  • The 49ers lost the game to the Atlanta Falcons.
  • McCaffrey told reporters after the game that he believes he will be 'alright' or 'fine'.

Reported by only some outlets

  • The New York Post reports that McCaffrey was the only healthy playmaker remaining on offense before his injury due to the absence of Mike Evans and Deebo Samuel.
  • CBS Sports and Newsweek report this was the 49ers' first loss of the season.
  • Yahoo Sports and the New York Post specify that McCaffrey was absent for the entire third offensive drive of the game.
  • CBS Sports notes McCaffrey finished the game with 7 carries for 39 yards and 6 receptions for 61 yards.

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